Sarcopenia associates with poor physical function and nosocomial infections in non-cancer populations ( Pichard et al, 2004 Cosquéric et al, 2006).
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below the healthy young adult mean ( Baumgartner et al, 1998), is associated with aging, inactivity and with a series of chronic diseases, including chronic renal failure, chronic obstructive pulmonary disease and cancer.
Sarcopenia, frequently defined as an absolute muscle mass <2 s.d. Sarcopenia predicts postoperative infections, inpatient rehabilitation care and consequently a longer LOS. In a multivariate model in patients ⩾65 years, sarcopenia was an independent predictor of both infection (odds ratio (OR) 4.6, (95% confidence interval (CI) 1.5, 13.9) P<0.01) and rehabilitation care (OR 3.1 (95% CI 1.04, 9.4) P<0.04). Inpatient rehabilitation was more common in sarcopenic patients overall (14.3% vs 5.6% P=0.024) and those ⩾65 years (24.1% vs 10.7%, P=0.06). Most (90%) inpatient rehabilitation care was in patients ⩾65 years.
Infection risk was greater for sarcopenic patients overall (23.7% vs 12.5% P=0.025), and especially those ⩾65 years (29.6% vs 8.8%, P=0.005). Length of stay was longer for sarcopenic patients overall (15.9☑4.2 days vs 12.3☙.8 days, P=0.038) and especially in those ⩾65 years (20.2☑6.9 days vs 13.1☘.3 days, P=0.008). Overall, 38.9% were sarcopenic 16.7% had an infection and 9.0% had inpatient rehabilitation care. Administrative hospitalisation data encompassing the index surgical admission, direct transfers for inpatient rehabilitation care and hospital re-admissions within 30 days was searched for International Classification of Disease (ICD)-10 codes for postoperative infections and inpatient rehabilitation care and used to calculate length of stay (LOS). Sarcopenia was assessed using preoperative computed tomography images. We tested whether sarcopenia predicts primary colorectal cancer resection outcomes in stage II–IV patients ( n=234). Skeletal muscle depletion (sarcopenia) predicts morbidity and mortality in the elderly and cancer patients.